look after‘照顾，照料，关心’，主要是对人在生活方面的照顾和料理。如，My mother is ill. I have to look after her at home.我妈病了。我不得不在家照看她。The nurse looked after the children very well.护士把这些孩子照顾得非常好。

take care of‘管理，保管，保护’，主要是对物品/动物的管理或保护。如，Can you take good care of these goods?你能看管好这些货物吗？“ Don't worry, I can take good care of your parrot while you are away.”said LinFeng.“别担心，你走了我会看护好你的鹦鹉的。”林风说。

有时这两个词组可以互用，表示‘看护...’. She usually looked after /took care of her classmates' clothes and other things while they were playing football. 她通常为同学看管衣物在他们踢足球的时候。